General

Ugo Basile designed the first industrial Rota-Rod in the 1960s, based on the 1957 paper by N.W Dunham and T.S Miya.

The name we coined soon became so popu-lar, now everybody knows this instrument as RotaRod!

The Rota-Rod is the reference test to screen drugs potentially active, or having side effects,on motor coordination.

The 47750 Rota-Rod NG (Next Generation), is an evolution of the original model and the re-sult of many years of research in cooperation with the latest development in behavioral and pharmacological research.

The 47750 combines the same functionality of the previous version, now considered the standard, with additional new features: sur-prisingly silent operation, much easier ex-perimental organization and data manage-ment.

Main Features

●SPEED: adjustable in the range 5-80 RPM,in steps of 1 RPM

●MODE: constant, ramp (accelerat- ing), multi-step ramp (NEW!)

●ROTATION: forward, reverse and rocking

●DRIVE: totally silent motor. Zero noise!

●CONTROLS: 4" 3 touch-screen to set and monitor the test

●X-PAD SOFTWARE: brand new, user-friendly version,to set the experiment and manage the results

●DETECTION: new design: trip-boxes to enclose the ani-mals, stainless-steel to ease sterilization

The Ugo Basile Rota-Rod NG consists of a 6cm diam. rod, su-itably machined to provide grip. Five flanges divide the four8.7cm lanes, enabling four rats to be simultaneously on test.When a rat falls off its rod section into the trip-box below, its endurance in RPMs is recorded. Height to fall is 30cm

A4”3 touch-screen shows the information for each section, and indicates the actual speed, (RPM):

What’s new

Physically similar to the previous versions, the new model fea- tures stainless-steel trip-boxes to facilitate cleaning and confi- ne the animals when they fall off the rod.

Totally new is the software included as standard, see paragra- phs below. Remote diagnosis and internet access are provided.

Experimental Configuration

Via the new X-PAD software, the operator can easily organize the experiment on her/his PC, and upload it to the Rota-Rod via the USB key.

Treatments, protocols, stages, animals, and various test featu-res (speed, mode, revolution, etc.) can be quickly defined and

Data Collection and Management

A basic version of the collected data can be viewed on the touch-screen; when transferred to PC via USB drive, test results appear in full version.

The X-PAD software automatically dlassifes the data, combi-ning configuration settings with test results. The user can add information, before or after the test. Results appear in a tree-like structure, where columns can be dragged and dropped to customize the layout.

Configurations and data are exported as Text, Excel or Pdf re-ports and can be saved to cloud via DropBox, OneDrive, Go-ogleDrive.

47850 Combo-Package for Mouse & Rat

You work with both rats and mice? You should consider the Combination Package 47850, including both Mouse and Rat

Connections

USB1    this USB 2.0 enables data exchange (protocols & results) with the PC, and allows firmware upgrades

USB2    the lower USB port accommodates the USB storage key and should not be removed

I/O       this D-SUB 15 connector provides TTL outputs for lane status, rotation and speed

COM    this USB-B 2.0 allows communication to the PC (for fac-tory use only)

ETH      the Ethernet connector is used for remote diagnosis and Internet access